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Background Cobalamin (vitamin B 12 ) deficiency is common in many low and middle-income countries.1 2 This is not surprising as the main source of vitamin B 12 is animal source foods, which are expensive and for cultural and religious reasons often not eaten at all

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terminal half-life 20-50 minutes) with a steady-state volume approximating total extracellular fluid, findings that justify loading schedules followed by less frequent injections once tissue stores exceed 2 mg

25 Castelli MC, Friedman K, Sherry J et al (2011) Comparing the efficacy and tolerability of a new daily oral vitamin B12 formulation and intermittent intramuscular vitamin B12 in normalizing low cobalamin levels: a randomized, open-label, parallel-group study